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Of chief or leading importance; prime, principal.

Chief, most important, or principal in extent, size, or strength; consisting of the largest part.

(of force, strength, etc.) Full, sheer, undivided.

(dialectal) Big; angry.

(nautical) Belonging to or connected with the principal mast in a vessel.

(obsolete) Great in size or degree; important, powerful, strong, vast.

(dialectal) Exceedingly, extremely, greatly, mightily, very, very much.

(slang) (to inject (a drug) directly into a vein).

(gaming) To mainly play a specific character or side, or with specific equipment, during a game.

(obsolete) To convert (a road) into a main or primary road.

(not in generic modern use) That which is chief or principal; the chief or main portion; the bulk, the greater part, gross.

(video gaming) The primary character that one plays in a video game in which one can play more than one character.

(Internet slang) A main account.

A large cable or pipe providing utility service to an area or a building, such as a water main or electric main.

(informal) (the principal dish of a meal).

(poetic) The high seas.

(dialectal) The mainland.

(nautical) (mainsail).

(except in might and main) Force, power, strength, violent effort.

(gaming) A hand or match in a game of dice.

(gaming) The largest throw in a match at dice; in the game of hazard, a number from one to nine called out by a person before the dice are thrown.

(gaming) A stake played for at dice.

(sports) A sporting contest or match, especially a cockfighting match.

A banker's shovel for coins.

(rare) A basket for gathering grapes.